Table 6

Hemodynamic and renal functional parameters at 60 and 180 min hemoperfusion of isolated kidney experimental groups and for the control group CON of living pigs


group
 CON
 A
 B
 C
 D
 E
RBF Bloodflow
 ml/min*100 g
 60 min
 ●
 339.9
 224.8
 244.5
 92.8
 153.8


SD
 •
 61.1
 28.4
 53.5
 25.8
 41.5


Signif.)*
BB;CC;DD;EE
 DD;E
 DD;EE
D


180 min
 ●
 363.0
 241.1
 285.5
 107.9
 160.1


SD
 •
 58.0
 19.4
 48.5
 28.4
 54.8
R Organ- Resistance
 mmHg/(ml/min*100 g)
 60 min
 ●
 0.29
 0.44
 0.37
 1.26
 0.61


SD
 •
 0.05
 0.06
 0.11
 0.49
 0.17


Signif.)*
BB;C;DD;EE
 DD;E
 DD;EE
DD


180 min
 ●
 0.28
 0.4
 0.29
 1.01
 0.61


SD
 •
 0.08
 0.03
 0.07
 0.31
 0.19
O2-cons Oxygen- Consumption
 μmol/min*100 g
 60 min
 ●
 263.9
 214.3
 141.6
 120.8
 206.4


SD
 •
 49.4
 22.3
 21.6
 27.6
 43.5


Signif.)*
BB;CC;DD;EE
 CC;DD
 EE
DD


180 min
 ●
 246.4
 213.6
 142.9
 116.2
 198.9


SD
 •
 39.4
 22.9
 19.0
 27.6
 36.8
VU Diuresis
 ml/min*100 g
 60 min
 0.87
 13.4
 7.2
 5.1
 0.7
 3.0


SD
 0.25
 6.1
 4.7
 3.8
 0.3
 2.3


Signif.)*
 AA
 BB;CC;DD;EE
 DD;E
 DD;E
DD


180 min
 ●
 14.4
 8.9
 5.7
 0.4
 3.2


SD
 •
 6.2
 5.1
 3.2
 0.3
 2.4
Clcrea Creatinine Clearance
 ml/min*100 g
 60 min
 76.1
 59.2
 27.6
 25.0
 1.64
 16.3


SD
 6.2
 13.9
 7.5
 10.6
 1.26
 8.2


Signif.)*
 A
 BB;CC;DD;EE
 DD;EE
 DD;E
DD


180 min
 ●
 65.9
 30.5
 24.1
 1.04
 15.2


SD
 •
 10.5
 4.8
 7.5
 0.89
 9.7
FF Filtration- Fraction
 %
 60 min
 ●
 22.5
 15.7
 14.9
 2.7
 13.3


SD
 •
 7.2
 6.7
 5.3
 2.5
 6.4


Signif.)*
 •
 B;CC;DD;EE
 DD
 DD
DD


180 min
 ●
 24.8
 16.4
 11.7
 1.1
 11.9


SD
 •
 7.2
 2.5
 3.6
 1.1
 7.2
RFH2O Water- Reabsorption- fraction
 %
 60 min
 98.9
 76.7
 72.4
 79.6
 35.4
 81.6


SD
 0.3
 9.5
 12.8
 13.2
 31.3
 17.2


Signif.)*
 AA
 DD
 DD;E
 DD
DD


180 min
 ●
 76.0
 70.9
 72.6
 36.1
 74.4


SD
 •
 11.1
 15.8
 23.3
 31.6
 30.0
RFNa Sodium- Reabsorption- fraction
 %
 60 min
 99,8
 82,3
 83,1
 86,8
 38,4
 88,7


SD
 0,1
 8,1
 10,4
 10,3
 24,5
 5,8


Signif.)*
 AA
 DD
 DD
 DD
DD


180 min
 ●
 80,9
 79,4
 81,0
 46,5
 89,4


SD
 •
 7,9
 13,9
 18,3
 31,4
 6,0
TNa Sodium- Reabsorption
 mmol/min*100 g
 60 min
 10,8
 6,83
 3,16
 2,91
 0,12
 1,98


SD
 1,0
 2,1
 1,0
 1,3
 0,1
 1,08


Signif.)*
 AA
 BB;CC;DD;EE
 DD
 DD
DD


180 min
 ●
 7,82
 3,43
 2,77
 0,09
 2,02


SD
 •
 1,6
 0,7
 1,0
 0,1
 1,1

(Signif* = Significance is denoted by capital letters labelling the resp. target group for comparison, as well as the level of significance: simple (p < 0.05) = single capital, high (p < 0.01) = twin capitals)

Unger et al. Journal of Occupational Medicine and Toxicology 2007 2:1   doi:10.1186/1745-6673-2-1

Open Data