Table 2

Exposure to chlorinated and aromatic hydrocarbons and lymphoma in total (n = 710 matched pairs)

Cases
 Controls
 Adj. ORa
 95% CI

N
 %
 N
 %

CHLORINATED HYDROCARBONS





Chlorinated hydrocarbons in total [ppm*yrs.]





     0 ppm*yrs.
 567
 79.9
 563
 79.3
 1.0
 -
     >0, <= 4.4 ppm*yrs.
 53
 7.5
 74
 10.4
 0.7
 0.5–1.0
     >4.4, <= 47.3 ppm*yrs.
 54
 7.6
 59
 8.3
 0.9
 0.6–1.3
     >47.3 ppm*yrs.
 29
 4.1
 14
 2.0
 2.1
 1.1–4.3
Trend test*




P = 0.03
Trichloroethene [ppm*yrs.]





     0 ppm*yrs.
 610
 85.9
 602
 84.4
 1.0
 -
     >0, <= 4.4 ppm*yrs.
 40
 5.6
 55
 7.7
 0.7
 0.4–1.1
     >4.4, <= 35 ppm*yrs.
 32
 4.5
 44
 6.2
 0.7
 0.5–1.2
     >35 ppm*yrs.
 21
 3.0
 9
 1.3
 2.1
 1.0–4.8
Trend test*




P = 0.14
Tetrachloroethene [ppm*yrs.]





     0 ppm*yrs.
 667
 93.9
 679
 95.6
 1.0
 -
     >0, <= 9.1 ppm*yrs.
 16
 2.3
 16
 2.3
 1.1
 0.5–2.3
     >9.1, <= 78.8 ppm*yrs.
 14
 2.0
 13
 1.8
 1.0
 0.5–2.2
     >78.8 ppm*yrs.
 6
 0.8
 2
 0.3
 3.4
 0.7–17.3
Trend test*




P = 0.12
Carbon tetrachlorine [ppm*yrs.]





     0 ppm*yrs.
 681
 95.9
 696
 98.0
 1.0
 -
     >0, <= 2.3 ppm*yrs.
 13
 1.8
 8
 1.1
 1.9
 0.7–5.2
     >2.3, <= 48.1 ppm*yrs.
 8
 1.1
 5
 0.7
 2.0
 0.6–6.9
     >48.1 ppm*yrs.
 1
 0.1
 1
 0.1
 -
 -
Trend test*




P = 0.48
Dichloromethane [ppm*yrs.]





     0 ppm*yrs.
 681
 95.9
 681
 95.9
 1.0
 -
     >0, <= 26.3 ppm*yrs.
 8
 1.1
 16
 2.3
 0.4
 0.2–1.0
     >26.3, <= 175 ppm*yrs.
 9
 1.3
 11
 1.5
 0.8
 0.3–1.9
     >175 ppm*yrs.
 5
 0.7
 2
 0.3
 2.2
 0.4–11.6
Trend test*




P = 0.40
AROMATIC HYDROCARBONS





Benzene [ppm*yrs.]





     0 ppm*yrs.
 591
 83.2
 590
 83.1
 1.0
     >0, <= 8.6 ppm*yrs.
 53
 7.5
 60
 8.5
 0.9
 0.6–1.3
     >8.6, <= 130 ppm*yrs.
 47
 6.6
 48
 6.8
 1.0
 0.7–1.5
     >130 ppm*yrs.
 12
 1.7
 12
 1.7
 0.8
 0.4–1.9
Trend test*




P = 0.87
Toluene [ppm*yrs.]





     0 ppm*yrs.
 538
 75.8
 545
 76.8
 1.0
     >0, <= 3.5 ppm*yrs.
 81
 11.4
 80
 11.3
 1.0
 0.7–1.5
     >3.5, <= 207 ppm*yrs.
 70
 9.9
 69
 9.7
 1.1
 0.7–1.5
     >207 ppm*yrs.
 14
 2.0
 16
 2.3
 0.8
 0.4–1.7
Trend test*




P = 0.74
Xylene [ppm*yrs.]





     0 ppm*yrs.
 549
 77.3
 552
 77.7
 1.0
     >0, <= 4.4 ppm*yrs.
 74
 10.4
 80
 11.3
 0.9
 0.7–1.3
     >4.4, <= 230 ppm*yrs.
 68
 9.6
 63
 8.9
 1.1
 0.7–1.6
     >230 ppm*yrs.
 12
 1.7
 15
 2.1
 0.8
 0.3–1.6
Trend test*




P = 0.56
Styrene [ppm*yrs.]





     0 ppm*yrs.
 542
 76.3
 541
 76.2
 1.0
     >0, <= 1.5 ppm*yrs.
 70
 9.9
 85
 12.0
 0.7
 0.5–1.0
     >1.5, <= 67.1 ppm*yrs.
 79
 11.1
 67
 9.4
 1.2
 0.8–1.7
     >67.1 ppm*yrs.
 12
 1.7
 17
 2.4
 0.6
 0.3–1.4
Trend test*




P = 0.43

Missing values were included as a separate category (not shown)

a Odds Ratio (OR) adjusted for smoking [packyears] and alcohol consumption [g per day]

* To calculate tests for trend, the exposure scores were included as continuous variables in the logistic regression model

Abbreviations: OR = odds ratio; CI = confidence interval; yrs. = years

Seidler et al. Journal of Occupational Medicine and Toxicology 2007 2:2   doi:10.1186/1745-6673-2-2

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