Table 3

Solvent exposure and HL, B-NHL, and T-NHL (unconditional logistic regression analysis)


Contr.
HL (n = 116)
B-NHL (n = 554)
T-NHL (n = 35)


N
N
Adj. ORa
95% CI
N
Adj. ORa
95% CI
N
Adj. ORa
95% CI

CHLORINATED HYDROCARBONS










Chlorinated hydrocarbons in total [ppm*yrs.]










     0 ppm*yrs.
563
101
1.0
-
436
1.0
-
26
1.0
-
     >0, <= 4.4 ppm*yrs.
74
5
0.3
0.1–0.8
45
0.8
0.5–1.2
2
0.5
0.1–2.5
     >4.4, <= 47.3 ppm*yrs.
59
8
0.8
0.3–2.1
42
0.9
0.6–1.4
4
1.5
0.4–5.0
     >47.3 ppm*yrs.
14
1
0.5
0.1–4.6
27
2.4
1.2–4.7
1
1.3
0.1–11.4
Trend test*


p = 0.63 (neg.)


p = 0.02


p = 0.23

Trichloroethene [ppm*yrs.]










     0 ppm*yrs.
602
10.4
1.0
-
47+
1.0
-
27
1.0
-
     >0, <= 4.4 ppm*yrs.
55
6
0.4
0.2–1.1
32
0.7
0.5–1.2
2
0.7
0.2–3.3
     >4.4, <= 35 ppm*yrs.
44
3
0.4
0.1–1.4
27
0.8
0.5–1.3
2
1.1
0.2–5.1
     >35 ppm*yrs.
9
2
2.0
0.4–10.5
17
2.3
1.0–5.3
2
4.7
0.8–26.1
Trend test*


p = 0.97


p = 0.08


p = 0.09

Tetrachloroethene [ppm*yrs.]










     0 ppm*yrs.
679
111
1.0
-
521
1.0
-
30
1.0
-
     >0, <= 9.1 ppm*yrs.
16
3
1.7
0.4–6.9
12
0.9
0.4–2.0
1
1.7
0.2–14.4
     >9.1, <= 78.8 ppm*yrs.
13
1
0.7
0.1–6.3
12
1.0
0.5–2.3
1
1.5
0.2–12.5
     >78.8 ppm*yrs.
2
-
-
-
5
3.2
0.6–16.7
1
-
-
Trend test*


p = 0.74 (neg.)


p = 0.16


p = 0.01

CTET [ppm*yrs.]










     0 ppm*yrs.
696
113
1.0
-
530
1.0
-
33
1.0
-
     >0, <= 2.3 ppm*yrs.
8
1
0.8
0.1–8.5
12
1.8
0.7–4.6
-
-
-
     >2.3, <= 48.1 ppm*yrs.
5
1
3.7
0.4–33.6
7
1.5
0.5–4.8
-
-
-
     >48.1 ppm*yrs.
1
-
-
-
1
-
-
-
-
-
Trend test*


p = 0.86 (neg.)


p = 0.60

-
-
-
DCM [ppm*yrs.]










     0 ppm*yrs.
681
113
1.0
-
531
1.0
-
32
1.0
-
     >0, <= 26.3 ppm*yrs.
16
2
0.7
0.2–3.6
6
0.4
0.2–1.1
-
-
-
     >26.3, <= 175 ppm*yrs.
11
-
-
-
8
0.9
0.3–2.3
1
1.2
0.1–10.9
     >175 ppm*yrs.
2
-
-
-
5
2.7
0.5–14.5
-
-
-
Trend test*


p = 0.24 (neg.)


p = 0.29


p = 0.5
(neg.)
AROMATIC HYDROCARBONS










Benzene [ppm*yrs.]










     0 ppm*yrs.
590
101
1.0
-
459
1.0
-
26
1.0
-
     >0, <= 8.6 ppm*yrs.
60
9
1.0
0.4–2.3
41
0.9
0.6–1.4
3
1.2
0.3–4.4
     >8.6, <= 130 ppm*yrs.
48
5
0.9
0.3–2.5
39
1.0
0.6–1.5
3
1.7
0.5–6.1
     >130 ppm*yrs.
12
-
-
-
11
1.0
0.4–2.3
1
1.7
0.2–15.0
Trend test*


P = 0.22 (neg.)



P = 0.50


P = 0.83
Toluene [ppm*yrs.]










     0 ppm*yrs.
545
88
1.0
-
421
1.0
-
24
1.0
-
     >0, <= 3.5 ppm*yrs.
80
19
1.2
0.7–2.3
56
1.0
0.7–1.5
6
1.6
0.6–4.4
     >3.5, <= 207 ppm*yrs.
69
8
0.9
0.4–2.0
60
1.1
0.8–1.6
2
0.8
0.2–3.5
     >207 ppm*yrs.
16
-
-

13
0.9
0.4–2.0
1
1.3
0.2–1.6
Trend test*


P = 0.30 (neg.)



P = 0.43


P = 0.72
Xylene [ppm*yrs.]










     0 ppm*yrs.
552
88
1.0
-
432
1.0
-
24
1.0
-
     >0, <= 4.4 ppm*yrs.
80
20
1.4
0.7–2.6
48
0.8
0.5–1.2
6
1.7
0.6–4.7
     >4.4, <= 230 ppm*yrs.
63
8
0.8
0.3–2.0
59
1.2
0.8–1.7
2
0.8
0.2–3.6
     >230 ppm*yrs.
15
-
-
-
11
0.9
0.4–1.9
1
1.5
0.2–13.0
Trend test*


P = 0.31 (neg.)



P = 0.34


P = 0.63
Styrene [ppm*yrs.]










     0 ppm*yrs.
541
91
1.0
-
423
1.0
-
23
1.0
-
     >0, <= 1.5 ppm*yrs.
85
11
0.4
0.2–0.8
53
0.8
0.6–1.2
6
1.3
0.5–3.6
     >1.5, <= 67.1 ppm*yrs.
67
13
1.5
0.7–3.1
62
1.2
0.8–1.7
4
1.6
0.5–4.8
     >67.1 ppm*yrs.
17
-
-
-
12
0.8
0.4–1.8
-
-
-
Trend test*


P = 0.26 (neg.)



P = 0.18


P = 0.41 (neg.)

Missing values were included as a separate category (not shown)

a Odds Ratio (OR) adjusted for age, sex, region, smoking [packyears] and alcohol consumption [g per day]

* To calculate tests for trend, the exposure scores were included as continuous variables in the logistic regression model; (neg.) means: p for trend for a negative association

Seidler et al. Journal of Occupational Medicine and Toxicology 2007 2:2   doi:10.1186/1745-6673-2-2

Open Data