Table 4

Solvent exposure and B-NHL subentities (unconditional logistic regression analysis)

Contr.
 DLBCL
(n = 158)
 FL
(n = 92)
 CLL
(n = 104)
 Multiple myeloma
(n = 76)
 Marginal zone lymphoma
(n = 38)

N
 N
 Adj. ORa
 95% CI
 N
 Adj. ORa
 95% CI
 N
 Adj. ORa
 95% CI
 N
 Adj. ORa
 95% CI
 N
 Adj. ORa
 95% CI
CHLORINATED HYDROCARBONS















Chlorinated hydrocarbons in total [ppm*yrs.]















     0 ppm*yrs.
 563
 132
 1.0
 -
 70
 1.0
 -
 78
 1.0
 -
 62
 1.0
 -
 27
 1.0
 -
     >0, <= 4.4 ppm*yrs.
 74
 10
 0.6
 0.3–1.2
 9
 1.4
 0.6–3.1
 11
 0.9
 0.4–1.9
 3
 0.4
 0.1–1.3
 4
 1.6
 0.5–5.1
     >4.4, <= 47.3 ppm*yrs.
 59
 9
 0.7
 0.3–1.5
 8
 1.7
 0.7–4.0
 9
 0.7
 0.3–1.6
 8
 1.0
 0.4–2.4
 3
 1.4
 0.4–5.3
     >47.3 ppm*yrs.
 14
 5
 1.8
 0.6–5.3
 5
 3.9
 1.3–12.1
 6
 1,8
 0.6–4.9
 2
 0.9
 0.2–4.4
 4
 7.0
 1.8–26.3
Trend test*


P = 0.02

P = 0.04

P = 0.88

P = 0.15

P = 0.008
Trichloroethene [ppm*yrs.]















     0 ppm*yrs.
 602
 139
 1.0
 -
 79
 1.0
 -
 86
 1.0
 -
 65
 1.0
 -
 32
 1.0
 -
     >0, <= 4.4 ppm*yrs.
 55
 6
 0.5
 0.2–1.2
 7
 1.3
 0.5–3.2
 10
 1.1
 0.5–2.4
 3
 0.5
 0.2–1.9
 2
 0.9
 1.2–4.3
     >4.4, <= 35 ppm*yrs.
 44
 7
 0.8
 0.3–1.8
 3
 0.7
 0.2–2.6
 6
 0.7
 0.3–1.7
 6
 1.0
 0.4–2.7
 2
 4.2
 0.8–23.9
     >35 ppm*yrs.
 9
 4
 2.6
 0.7–3.0
 3
 3.2
 0.8–12.9
 2
 0.9
 0.2–4.5
 1
 0.7
 0.1–5.5
 2
 4.2
 0.8–23.9
Trend test*


P = 0.03

P = 0.16

P = 0.46 (neg.)

P = 0.43 (neg.)

P = 0.15
Tetrachloroethene [ppm*yrs.]















     0 ppm*yrs.
 679
 146
 1.0
 -
 90
 1.0
 -
 101
 1.0
 -
 33
 1.0
 -
1.0
 -
     >0, <= 9.1 ppm*yrs.
 16
 3
 0.9
 0.3–3.9
 2
 1.2
 0.3–5.5
 1
 -
 -
 3
 1.8
 0.5–6.7
 1
 -
 -
     >9.1, <= 78.8 ppm*yrs.
 13
 6
 2.1
 0.8–5.9
 -

2
 0.6
 0.1–2.8
 -
 -
 -
 3
 4.2
 1.02–17.5
     >78.8 ppm*yrs.
 2
 1
 2.3
 0.2–26.0
 -

-
 -
 -
 -
 -
 -
 1
 -
 -
Trend test*


P = 0.19

P = 0.43 (neg.)

P = 0.6

P = 0.34 (neg.)

P = 0.10
CTET [ppm*yrs.]















     0 ppm*yrs.
 696
 153
 1.0
 -
 87
 1.0
 -
 98
 1.0
 -
 72
 1.0
 -
 37
 1.0
 -
     >0, <= 2.3 ppm*yrs.
 8
 1
 0.7
 0.1–6.1
 4
 5.0
 1.4–18.3
 5
 2.7
 1.8–8.9
 -
 -
 -
 -
 -
 -
     >2.3, <= 48.1 ppm*yrs.
 5
 2
 1.6
 0.3–8.9
 1
 2.1
 0.2–19.4
 -
 -
 -
 3
 4.5
 0.57–20.9
 1
 3.6
 0.4–34.6
     >48.1 ppm*yrs.
 1
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
 -
Trend test*


P = 0.75

P = 0.83

P = 0.38

P = 0.83

P = 0.98
DCM [ppm*yrs.]















     0 ppm*yrs.
 681
 150
 1.0
 -
 88
 1.0
 -
 100
 1.0
 -
 74
 1.0
 -
 36
 1.0
 -
     >0, <= 26.3 ppm*yrs.
 16
 3
 0.8
 0.2–2.9
 1
 0.5
 0.1–4.3
 1
 0.3
 0.04–2.4
 -
 -
 -
 1
 1.5
 0.2–11.9
     >26.3, <= 175 ppm*yrs.
 11
 2
 0.9
 0.2–4.2
 2
 1.5
 0.3–7.4
 2
 0.8
 0.2–3.9
 -
 -
 -
 -
 -
 -
     >175 ppm*yrs.
 2
 1
 -
 -
 1
 -
 -
 1
 -
 -
 1
 -
 -
 1
 -
 -
Trend test*


P = 0.45

P = 0.20

P = 0.78

P = 0.19

P = 0.10
AROMATIC HYDROCARBONS















Benzene [ppm*yrs.]















     0 ppm*yrs.
 590
 136
 1.0
 -
 73
 1.0
 -
 80
 1.0
 -
 62
 1.0
 -
 32
 1.0
 -
     >0, <= 8.6 ppm*yrs.
 60
 9
 0.7
 0.3–1.4
 10
 1.8
 0.8–3.8
 8
 0.8
 0.4–1.8
 6
 1.0
 0.4–2.4
 2
 0.7
 0.2–3.0
     >8.6, <= 130 ppm*yrs.
 48
 10
 0.9
 0.4–1.9
 7
 1.5
 0.6–3.5
 14
 1.6
 0.8–3.2
 4
 0.7
 0.2–2.0
 3
 1.1
 0.3–3.8
     >130 ppm*yrs.
 12
 1
 0.3
 0.04–2.6
 2
 1.3
 0.3–6.4
 2
 0.7
 0.1–3.1
 3
 1.8
 0.5–6.8
 1
 1.4
 0.2–11.8
Trend test*


P = 0.52 (neg.)

P = 0.51

P = 0.48

P = 0.54

P = 0.32
Toluene [ppm*yrs.]















     0 ppm*yrs.
 545
 122
 1.0
 -
 66
 1.0
 -
 76
 1.0
 -
 59
 1.0
 -
 27
 1.0
 -
     >0, <= 3.5 ppm*yrs.
 80
 18
 1.1
 0.6–2.0
 8
 1.1
 0.5–2.4
 11
 0.9
 0.4–1.8
 6
 0.8
 0.3–1.9
 4
 1.0
 0.3–3.3
     >3.5, <= 207 ppm*yrs.
 69
 14
 1.0
 0.5–1.9
 16
 2.6
 1.4–5.1
 15
 1.3
 0.7–2.4
 7
 0.9
 0.4–2.0
 6
 1.9
 0.7–5.1
     >207 ppm*yrs.
 16
 2
 0.6
 0.1–2.5
 2
 1.1
 0.2–5.3
 2
 0.5
 0.1–2.4
 3
 1.4
 0.4–5.2
 1
 1.1
 0.1–9.5
Trend test*


P = 0.87

P = 0.48

P = 0.48

P = 0.48

P = 0.48
Xylene [ppm*yrs.]















     0 ppm*yrs.
 552
 127
 1.0
 -
 66
 1.0
 -
 79
 1.0
 -
 59
 1.0
 -
 27
 1.0
 -
     >0, <= 4.4 ppm*yrs.
 80
 13
 0.8
 0.4–1.5
 7
 1.0
 0.4–2.3
 9
 0.7
 0.3–1.5
 6
 0.8
 0.3–1.9
 5
 1.4
 0.5–4.0
     >4.4, <= 230 ppm*yrs.
 63
 14
 1.1
 0.6–2.0
 17
 3.0
 1.6–5.8
 15
 1.3
 0.7–2.5
 7
 0.9
 0.4–2.2
 5
 1.8
 0.6–4.9
     >230 ppm*yrs.
 15
 2
 0.6
 0.1–2.6
 2
 1.3
 0.3–6.2
 1
 0.3
 0.04–2.2
 3
 1.5
 0.4–5.8
 1
 1.3
 0.2–10.5
Trend test*


P = 0.95

P = 0.33

P = 0.47

P = 0.36

P = 0.40
Styrene [ppm*yrs.]















     0 ppm*yrs.
 541
 117
 1.0
 -
 60
 1.0
 -
 81
 1.0
 -
 60
 1.0
 -
 31
 1.0
 -
     >0, <= 1.5 ppm*yrs.
 85
 15
 0.8
 0.4–1.5
 12
 1.1
 0.5–2.1
 10
 1.0
 0.5–2.2
 6
 0.8
 0.3–1.9
 4
 1.0
 0.3–3.0
     >1.5, <= 67.1 ppm*yrs.
 67
 19
 1.3
 0.7–2.3
 17
 2.2
 1.2–4.0
 11
 1.1
 0.5–2.2
 8
 1.0
 0.5–2.4
 3
 0.8
 0.2–2.6
     >67.1 ppm*yrs.
 17
 5
 1.5
 0.5–4.4
 3
 1.6
 0.5–6.0
 2
 0.5
 0.2–2.3
 1
 0.5
 0.1–3.8
 -
 -
 -
Trend test*


P = 0.03

P = 0.20

P = 0.37

P = 0.85

P = 0.28

Missing values were included as a separate category (not shown)

a Odds Ratio (OR) adjusted for age, sex, region, smoking [packyears] and alcohol consumption [g per day]

* To calculate tests for trend, the exposure scores were included as continuous variables in the logistic regression model

Abbreviations: OR = odds ratio; CI = confidence interval; yrs. = years

Seidler et al. Journal of Occupational Medicine and Toxicology 2007 2:2   doi:10.1186/1745-6673-2-2

Open Data