Table 1 |
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|
The correlation between IFN-γ and IL-12p70 released by human PBMC. |
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|
Cadmium acetate |
Mercuric chloride |
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|
|
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|
mAb-stimulation |
hkSE-stimulation |
mAb-stimulation |
hkSE-stimulation |
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|
Donor |
r |
p |
r |
p |
r |
p |
r |
p |
|
|
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|
1 |
0.84 |
0.0006 |
0.41 |
0.1826 |
0.85 |
<0.0001 |
0.72 |
0.0024 |
|
2 |
0.83 |
0.001 |
0.51 |
0.0893 |
0.96 |
<0.0001 |
0.73 |
0.0022 |
|
3 |
0.95 |
<0.0001 |
0.06 |
0.8629 |
0.94 |
<0.0001 |
0.80 |
0.0004 |
|
4 |
0.83 |
0.001 |
0.70 |
0.0114 |
0.89 |
<0.0001 |
0.70 |
0.0034 |
|
5 |
0.90 |
<0.0001 |
0.86 |
0.0003 |
0.27 |
0.3278 |
0.87 |
<0.0001 |
|
6 |
0.90 |
<0.0001 |
0.72 |
0.0082 |
0.96 |
<0.0001 |
0.85 |
<0.0001 |
|
7 |
0.64 |
0.0261 |
0.50 |
0.1006 |
0.91 |
<0.0001 |
0.44 |
0.0983 |
|
8 |
0.90 |
<0.0001 |
0.87 |
0.0003 |
0.63 |
0.0121 |
0.86 |
<0.0001 |
|
9 |
0.93 |
<0.0001 |
0.76 |
0.0045 |
0.16 |
0.5499 |
0.26 |
0.3549 |
|
10 |
0.63 |
0.0283 |
0.83 |
0.001 |
0.84 |
<0.0001 |
0.90 |
<0.0001 |
|
11 |
0.97 |
<0.0001 |
0.23 |
0.4201 |
||||
|
12 |
0.94 |
<0.0001 |
0.78 |
0.0007 |
||||
|
13 |
0.80 |
0.0016 |
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|
14 |
0.94 |
<0.0001 |
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|
|
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|
Mean |
1 |
<0.0001 |
0.59 |
0.0415 |
0.93 |
<0.0001 |
0.71 |
0.0032 |
|
|
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|
Human peripheral blood mononuclear cells (PBMC) were cultured for 24 hr in absence or presence of cadmium acetate or mercuric chloride and stimulated either by monoclonal antibodies (mAb: anti-CD3/anti-CD28/anti-CD40) or heat-killed Salmonella enterica serovar Enteritidis (hkSE). Cytokine values were evaluated in cell supernatants using ELISA; r represents Spearman correlation values estimated for each sample. The last raw represents the Spearman correlation between the mean values of IFN-γ and IL-12p70 of all investigated donors. |
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|
Hemdan Journal of Occupational Medicine and Toxicology 2008 3:25 doi:10.1186/1745-6673-3-25 |
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